Clinical significance of gastritis cystica profunda and its association with...
CONCLUSIONS:Patients with gastric cancer who had GCP had clinicopathologic features that differed from the features observed in patients without GCP. GCP was associated significantly with EBV‐positive...
View ArticleMetastatic basal cell carcinoma in the era of hedgehog signaling pathway...
The objective of the current review, in which the authors evaluated the time from the first BCC diagnosis to metastasis, location of disease, and radiographic features, was to contribute to the general...
View ArticlePhase 1/2 trial of single‐session stereotactic body radiotherapy for...
CONCLUSIONS:Data from this phase 1/2 supported an expanded indication for SBRT as first‐line treatment of spinal metastases in selected patients. The authors concluded that additional studies that can...
View ArticleHormone receptor status influences the locoregional benefit of trastuzumab in...
CONCLUSIONS:Among patients with HR+/HER2+ disease, treatment with trastuzumab reduces LRR risk to the more favorable outcome of patients with HR+/HER2− disease. In contrast, the increased LRR risk...
View ArticleSmall median tumor diameter at cure threshold (< 20 mm) among aggressive...
We describe a novel simulation framework in which tumor progression depends on cellular proliferation and mutation within a stem cell compartment of the tumor. We fit this model to randomized trial...
View ArticleQuantification of PKC family genes in sporadic breast cancer by qRT‐PCR:...
AbstractDrugs targeting protein kinase C (PKC) show promising therapeutic activity. However, little is known about the expression patterns of the 11 PKC genes in human tumors, and the clinical...
View ArticleBody size and risk of differentiated thyroid carcinomas: findings from the...
AbstractResults from case‐control and prospective studies suggest a moderate positive association between obesity and height and differentiated thyroid carcinoma (TC). Little is known on the...
View ArticleNovel therapy for therapy‐resistant mantle cell lymphoma: multipronged...
AbstractMantle cell lymphoma (MCL) is one of the most aggressive B‐cell lymphomas with a median patient survival of only five to seven years. The failure of existing therapies is mainly due to disease...
View ArticleSingle treatment of non‐melanoma skin cancers using a pulsed‐dye laser with...
ConclusionsThe results of our pilot study suggest that BCCs and SCCIS can be cleared in a single treatment using a pulsed‐laser in a stacked pulse setting. However, given the small sample size of this...
View ArticleImmunoediting the cancer genome – a new approach for personalized cancer...
(Source: Pigment Cell Research)
View ArticleAmplification and high-level expression of heat shock protein 90 marks...
Conclusions: Up-regulated HSP90 mRNA expression represents a confluence of genomic vulnerability that renders HER2 negative breast cancers more aggressive, resulting in poor prognosis. Targeting breast...
View ArticleIn vivo breast cancer characterization imaging using two monoclonal...
Conclusions: Multi-color target-specific fluorescence breast cancer imaging can be achieved in vivo by employing two activatable fluorescent probes administered as a cocktail. The images allowed us to...
View ArticleBody mass index and survival after breast cancer diagnosis in Japanese women
Background: Body mass index (BMI) may be an important factor affecting breast cancer outcome. Studies conducted mainly in Western countries have reported a relationship between higher BMI and a higher...
View ArticleEarly entry and deformation of macropinosomes correlates with high efficiency...
ConclusionsWe have shown that the existence of R10B/DNA complexes in macropinosomes at the early stages of gene delivery correlates with high efficiency R10B‐mediated gene delivery. This finding will...
View ArticleInhibition of Ca2+/Calmodulin-dependent protein kinase II reverses...
Conclusions: These results suggest that CaMKII is involved in the oxaliplatin-induced mechanical allodynia, and trifluoperazine may be useful for the treatment of oxaliplatin-induced peripheral...
View ArticleEffects of chemotherapy during pregnancy on the maternal and fetal heart
ConclusionA specific strategy for monitoring fetal and maternal chemotherapy‐induced cardiotoxicity is suggested. Prospective data are needed on the long‐term effects of chemotherapy in both mother and...
View Article
